An age reversing drug might be on the horizons after an experimental Alzheimer’s drug had a surprise side-effect of making old mice young.
The new drug was so successful at reversing the years in laboratory mice that human tests are already being planned for 2016.
Researchers at the Salk Institute in California made the find after targeting their study on Alzheimer’s largest risk factor, old age.
When the rodents were treated with the new medicine, referred to as J147, it enhanced cognition and memory and made blood vessels in the brain healthier.
It also enhanced their physical look, making them appear younger.
Researchers never anticipated the therapy to slow growth, but hailed them a welcome advantage if the drug becomes safe for use by Alzheimer’s patients.
The tested group of rodents, one young, a second old and the third aged but fed J147 as they become old.
The team afterward measured how each gene in the brain responded as the mice, a breed that gets old fast, got older.
They discovered that the old mice, which got J147, did better on memory and other tests for cognition and as well showed more robust motor motions.
The mice treated with the drug as well had lesser symptoms of Alzheimer’s.
Astonishingly, the way the gene illustration and metabolism of those aged mice treated with J147 was much like the ones from the young mice.
One more significant effect was that J147 stopped blood leakage from the microvessels in the brains of older mice.
The researchers had already discovered J147 could stop as well as reverse memory loss in mice, which have a version of the passed down type of Alzheimer’s.
However, this type of illness has only around 1% of cases with advancing years the major risk factor for everyone else.
Approximately 850, 000 people are living with dementia in Britain, two-thirds of whom have Alzheimer’s.
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